AERIFY-3: Mechanistic Study of Itepekimab on Airway Inflammation in COPD

An open-label Phase 2a study of how itepekimab affects airway inflammation over 12 weeks in former and current smokers with COPD.

Phase 2Phase
CompletedStatus
NCT05326412 ↗ClinicalTrials.gov

About the study

AERIFY-3 was an exploratory Phase 2a study of how itepekimab, an investigational anti-IL-33 antibody, works on airway inflammation in COPD. Participants received 12 weeks of treatment, and researchers studied samples from the airways and nose to understand the medicine's effects in former and current smokers.

Who took part

The study enrolled people who:

  • Were 40 to 70 years old
  • Had COPD with chronic bronchitis symptoms and a smoking history of at least 10 pack-years

Status at Veritas

This study has been completed. It is no longer enrolling, and it is listed here as part of Veritas Clinical Research's track record as a research site.

Learn more

The full study record, including all eligibility criteria and outcome measures, is on ClinicalTrials.gov (NCT05326412).

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