AERIFY-1: Itepekimab in Former Smokers With Moderate-to-Severe COPD

A Phase 3 study of itepekimab, an anti-IL-33 antibody, compared with placebo for reducing COPD flare-ups in former smokers with moderate-to-severe COPD.

Phase 3Phase
CompletedStatus
NCT04701983 ↗ClinicalTrials.gov

About the study

AERIFY-1 was a Phase 3 study of itepekimab, an investigational antibody that blocks interleukin-33 (IL-33), compared with placebo in former smokers with moderate-to-severe COPD. The main goal was to see whether it reduced moderate or severe COPD flare-ups. Lung function and respiratory symptoms were also measured.

Who took part

The study enrolled people who:

  • Were 40 to 85 years old
  • Had moderate-to-severe COPD and were former smokers

Status at Veritas

This study has been completed. It is no longer enrolling, and it is listed here as part of Veritas Clinical Research's track record as a research site.

Learn more

The full study record, including all eligibility criteria and outcome measures, is on ClinicalTrials.gov (NCT04701983).

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