NIMBLE: Switching to Depemokimab From Mepolizumab or Benralizumab in Severe Eosinophilic Asthma

A Phase 3 study of whether switching to depemokimab works as well as continuing mepolizumab or benralizumab in people with severe eosinophilic asthma.

Phase 3Phase
CompletedStatus
NCT04718389 ↗ClinicalTrials.gov

About the study

NIMBLE was a Phase 3 study for people with severe eosinophilic asthma who were already benefiting from mepolizumab or benralizumab. It tested whether switching to depemokimab (GSK3511294), an investigational long-acting biologic, controlled asthma attacks as well as staying on the current biologic.

Who took part

The study enrolled people who:

  • Were 12 years of age or older
  • Had severe eosinophilic asthma and had been benefiting from mepolizumab or benralizumab

Status at Veritas

This study has been completed. It is no longer enrolling, and it is listed here as part of Veritas Clinical Research's track record as a research site.

Learn more

The full study record, including all eligibility criteria and outcome measures, is on ClinicalTrials.gov (NCT04718389).

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